A synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the pineal gland extract epithalamin, studied in telomerase-activation and geroprotective research.
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Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from research into epithalamin, a pineal gland extract studied for decades by the St. Petersburg Institute of Bioregulation and Gerontology. Its primary research interest is as a telomerase activator: in aging human fibroblast cultures, epitalon has been shown to normalize progressively shortening telomeres, apparently by upregulating TERT gene expression rather than acting directly on the telomerase enzyme itself. It's studied within the broader Khavinson peptide bioregulator class, a research program focused on tissue-specific short peptides and cellular aging, with foundational work originating largely from Russian laboratories.
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