A pentadecapeptide derived from a gastric-protective protein sequence, studied in tissue-repair and angiogenesis research models.
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BPC-157 is a synthetic 15-amino-acid peptide derived from a protective protein found in human gastric juice, first described in the early 1990s as "Body Protection Compound." Preclinical studies — largely in rodent models — report that it promotes new blood-vessel formation by upregulating the VEGFR2 receptor, and accelerates healing across a striking range of tissue-injury models, from NSAID-induced gastric ulcers to Achilles tendon transection. In tendon fibroblasts specifically, BPC-157 has been shown to sharply increase growth hormone receptor expression, a proposed mechanism behind its tissue-repair effects. It remains one of the most-studied peptides in animal models, though controlled human-trial data is still limited.
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